{"id":11535,"date":"2023-01-15T09:00:00","date_gmt":"2023-01-15T06:00:00","guid":{"rendered":"https:\/\/suymerbir.org.tr\/?p=11535"},"modified":"2025-08-19T09:16:13","modified_gmt":"2025-08-19T06:16:13","slug":"alabalik-bagisikliginda-yeni-kesif","status":"publish","type":"post","link":"https:\/\/www.suymerbir.org.tr\/en\/alabalik-bagisikliginda-yeni-kesif.html","title":{"rendered":"G\u00f6kku\u015fa\u011f\u0131 Alabal\u0131\u011f\u0131&#8217;n\u0131n ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131nda yeni ke\u015fif"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\">New Mexico \u00dcniversitesi&#8217;ndeki Salinas Laboratuar\u0131&#8217;ndan ara\u015ft\u0131rmac\u0131lar, G\u00f6kku\u015fa\u011f\u0131 Alabal\u0131\u011f\u0131&#8217;n\u0131n burun bo\u015fluklar\u0131nda bir ba\u011f\u0131\u015f\u0131kl\u0131k yap\u0131s\u0131 tespit etti. Bu da su \u00fcr\u00fcnleri yeti\u015ftiricili\u011finde kullan\u0131lacak olan a\u015f\u0131lar\u0131n daha iyi bir hale gelmesine katk\u0131 sa\u011flayacak.<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">T\u00fcrkiye&#8217;de, yeti\u015ftiricili\u011fi en fazla yap\u0131lan i\u00e7 su bal\u0131\u011f\u0131 t\u00fcr\u00fcn\u00fcn G\u00f6kku\u015fa\u011f\u0131 Alabal\u0131\u011f\u0131 oldu\u011funu d\u00fc\u015f\u00fcn\u00fcrsek, alabal\u0131k konusunda yap\u0131lan her ara\u015ft\u0131rma \u00fclkemizdeki yeti\u015ftiricili\u011fi iyi y\u00f6nde etkileyecek.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bununla birlikte, bal\u0131klarla memelilerin ba\u011f\u0131\u015f\u0131kl\u0131k sistemlerinin benzerliklerinden haberdar olmakla birlikte, ba\u015fta anatomik y\u00f6nden farkl\u0131l\u0131klar\u0131n varl\u0131\u011f\u0131 nedeniyle, memeli olmayan omurgal\u0131lar\u0131n ba\u011f\u0131\u015f\u0131kl\u0131k sistemleri konusunda yeteri kadar bilgi sahibi de\u011filiz.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bu seferki ara\u015ft\u0131rma d\u00fcnyan\u0131n \u00f6te yan\u0131ndan. New Mexico \u00dcniversitesi\u2019ndeki ara\u015ft\u0131rmac\u0131lar\u0131n G\u00f6kku\u015fa\u011f\u0131 Alabal\u0131\u011f\u0131\u2019n\u0131n (<em>Oncorhynchus mykiss<\/em>) burun yap\u0131s\u0131nda ke\u015ffettikleri bu nazal ba\u011f\u0131\u015f\u0131kl\u0131k yap\u0131s\u0131n\u0131n; insanlarda, a\u015f\u0131land\u0131\u011f\u0131nda veya enfekte oldu\u011funda meydana gelen bir reaksiyon olan <em>germinal merkezlerin<\/em> molek\u00fcler \u00f6zelliklerine sahip oldu\u011fu ke\u015ffedildi.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Germinal merkez reaksiyonlar\u0131 genellikle a\u015f\u0131 yan\u0131tlar\u0131 i\u00e7in belirte\u00e7ler olarak kullan\u0131l\u0131yor.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Biyoloji profes\u00f6r\u00fc ve ba\u015fkan yard\u0131mc\u0131s\u0131 Irene Salinas, <em>\u0130nsanlarda, farelerde ve ku\u015flarda lenfoid yap\u0131larda germinal merkez reaksiyonlar\u0131n\u0131 biliyorduk, ancak bal\u0131k ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin mimarisinin bu t\u00fcr yap\u0131lara sahip oldu\u011funu d\u00fc\u015f\u00fcnm\u00fcyorduk<\/em> diyor. <em>Biz de dahil olmak \u00fczere bir\u00e7ok ki\u015fi onlar\u0131 arad\u0131, ancak esas olarak do\u011fru aletlerin olmamas\u0131 nedeniyle onlar\u0131 bulamad\u0131k<\/em>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ara\u015ft\u0131rma, Journal of Immunology&#8217;nin <a rel=\"noreferrer noopener\" href=\"https:\/\/journals.aai.org\/jimmunol\/article\/209\/11\/2215\/237337\/A-Novel-Organized-Nasopharynx-Associated-Lymphoid\" target=\"_blank\">Aral\u0131k say\u0131s\u0131nda bir makale<\/a>de yay\u0131nland\u0131. UNM Biyoloji Doktora \u00f6\u011frencisi Ben Garcia ba\u015f yazar iken Fen Dong, Elisa Casadei, Pedro A Castrillo, Julien Resseguier ve Idaho \u00dcniversitesi&#8217;ndeki i\u015fbirlik\u00e7iler de bu ekibin bir par\u00e7as\u0131 ve makalenin ortak yazarlar\u0131.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Germinal merkezlerdeki B h\u00fccreleri, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin bir par\u00e7as\u0131 ve, vir\u00fcsler ve bakterilerle sava\u015fmak i\u00e7in antikorlar olu\u015fturarak ara\u015ft\u0131rmac\u0131lara, bal\u0131klar\u0131n a\u015f\u0131lara nas\u0131l tepki verdi\u011fine bir g\u00f6z atma imkan\u0131 veriyor.<br>Bu yap\u0131lar\u0131n memeli \u00fcreme merkezleri gibi i\u015flev g\u00f6rd\u00fc\u011f\u00fcne dair nihai kan\u0131t\u0131n \u00fcretilmesi gerekiyor. Ara\u015ft\u0131rma, alabal\u0131k nazal germinal merkez benzeri yap\u0131lar i\u00e7indeki B h\u00fccrelerinin enfeksiyon veya a\u015f\u0131lamaya yan\u0131t olarak olgunla\u015ft\u0131\u011f\u0131n\u0131 g\u00f6steren bir dizi devam eden deneyi i\u00e7eriyor. Bu, repertuar olarak bilinen B h\u00fccresi resept\u00f6rlerinin dizilerini inceleyerek yap\u0131lmakta. Bir a\u015f\u0131ya yan\u0131t olarak belirli B h\u00fccrelerinin klonal geni\u015flemesinin g\u00f6sterilmesi, bulmacan\u0131n hen\u00fcz tamamlanmam\u0131\u015f olan kritik bir par\u00e7as\u0131.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New Mexico \u00dcniversitesi&#8217;ndeki Salinas Laboratuar\u0131&#8217;ndan ara\u015ft\u0131rmac\u0131lar, G\u00f6kku\u015fa\u011f\u0131 Alabal\u0131\u011f\u0131&#8217;n\u0131n burun bo\u015fluklar\u0131nda bir ba\u011f\u0131\u015f\u0131kl\u0131k yap\u0131s\u0131 tespit etti. Bu da su&#8230;<\/p>\n","protected":false},"author":2,"featured_media":11537,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":"","_uag_custom_page_level_css":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"footnotes":""},"categories":[33,36],"tags":[],"class_list":["post-11535","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","category-su-urunleri-yetistiriciligi"],"featured_image_src":null,"author_info":{"display_name":"Kaan Ugrasiz","author_link":"https:\/\/www.suymerbir.org.tr\/en\/author\/travego"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>G\u00f6kku\u015fa\u011f\u0131 Alabal\u0131\u011f\u0131&#039;n\u0131n ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131nda yeni ke\u015fif<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.suymerbir.org.tr\/en\/alabalik-bagisikliginda-yeni-kesif.html\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:locale:alternate\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"G\u00f6kku\u015fa\u011f\u0131 Alabal\u0131\u011f\u0131&#039;n\u0131n ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131nda yeni ke\u015fif\" \/>\n<meta property=\"og:description\" content=\"New Mexico \u00dcniversitesi&#8217;ndeki Salinas Laboratuar\u0131&#8217;ndan ara\u015ft\u0131rmac\u0131lar, G\u00f6kku\u015fa\u011f\u0131 Alabal\u0131\u011f\u0131&#8217;n\u0131n burun bo\u015fluklar\u0131nda bir ba\u011f\u0131\u015f\u0131kl\u0131k yap\u0131s\u0131 tespit etti. 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